Oral Presentation Royal Australian Chemical Institute National Congress 2026

meso-Tetraarylporphyrins peripherally functionalized with Ru(dppe)2Cl alkynyl complexes: remarkable nonlinear optical properties and potential use in anti-cancer therapy (136716)

Limiao Shi 1 , Viktoriia Gorbunova 2 , Olivier Mongin 2 , Christine O Paul-Roth 1 , Sandrine Cammas-Marion 3 , Franck Camerel 4 , Maciej Lorenc 5 , Thomas Pezeril 5 , Leszek M Mazur 6 , Katarzyna Matczyszyn 6 , Magali Gary-Bobo 7 , Mark G Humphrey 8 , Frédéric Paul 4
  1. Institute of Chemistry, Univ Rennes, INSA Rennes, Rennes, F-35000, France
  2. Institute of Chemistry, Univ Rennes, Rennes, F-35000, France
  3. Institute of Chemistry, Univ Rennes, ENSCR, Rennes, F-35000, France
  4. Institute of Chemistry, Univ Rennes, CNRS, Rennes, France
  5. Institute of Physics, Univ Rennes, CNRS, Rennes, F-35000, France
  6. Faculty of Chemistry, Wroclaw Univ. of Science and Technology, Wroclaw, 50-370 , Poland
  7. IBMM, Univ. Montpellier, CNRS, ENSCM, 34293, Montpellier, France
  8. Research School of Chemistry, Australian National Univ., Canberra, ACT, Australia

Tetra-arylporphyrins constitute appealing molecular platforms endowed with interesting linear and nonlinear optical properties. In particular, when associated to electron-rich alkynyl complexes, the resulting molecules can present remarkable properties for developing molecular-based devices for electronics or photonics,[1] such as for instance redox-switchable fluorophores[2] or electrochromic NLO-phores[3]. We will first recall how recent studies on well-designed molecular model such as M1-3 allowed us to reach a better understanding of the role of the particular [Ru(dppe)2Cl] alkynyl unit on the photonic properties, at the molecular level,[4] before showing how this knowledge can be used to build porphyrin-based nonlinear chromophores such as 1-2a-b that might present an applied potential in the field of anti-cancerous phototherapy.

 

  1. [1] (a) Marques-Gonzales, S.; Low, P. J. Aust. J. Chem. 2016, 69, 244. (b) Grelaud, G.; Cifuentes, M. P.; Paul, F.; Humphrey, M. G. J. Organomet. Chem. 2014, 751, 181.
  2. [2] Merhi, A.; Grelaud, G.; Green, K. A.; Ngo, H. M.; Reynolds, M.; Ledoux, I.; Barlow, A.; Wang, G.; Cifuentes, M. P.; Humphrey, M. G.; Paul, F.; Paul-Roth, C. O. Dalton Trans. 2015, 44, 7748.
  3. [3] Merhi, A.; Grelaud, G.; Morshedi, M.; Abid, S.; Green, K. A.; Barlow, A.; Groizard, T.; Kahlal, S.; Halet, J.-F.; Ngo, H. M.; Ledoux-Rak, I.; Cifuentes, M. P.; Humphrey, M. G.; Paul, F.; Paul-Roth, C. O. Dalton Trans. 2018, 47, 11123 (and refs therein).
  4. [4] (a) Triadon, A.; Grelaud, G.; Richy, N.; Mongin, O.; Moxey, G. J.; Dixon, I. M.; Yang, X.; Wang, G.; Barlow, A.; Rault-Berthelot, J.; Cifuentes, M. P.; Humphrey, M. G.; Paul, F. Organometallics 2018, 35, 2245; (b) Cherruault, V.; Camerel, F.; Morin, J.; Triadon, A.; Godin, N.; Lefort, R.; Mongin, O.; Bergamini, J.-F.; Vacher, A.; Humphrey, M. G.; Lorenc, M.; Paul, F.; Pezeril, T., J. Chem. Phys. 2025, 163, 024201.